TCA+recall

= TCA recall =

[|Amitriptyline] [|Clomipramine] [|Dothiepin] [|Doxepin] [|Imipramine] [|Nortriptyline] [|Trimipramine]

TCAs inhibit reuptake of noradrenaline and serotonin into presynaptic terminals. Although unrelated to the therapeutic effects of the TCAs, they also block cholinergic, histaminergic, alpha1-adrenergic and serotonergic receptors. Clomipramine has a greater effect on serotonin transport than other TCAs.
 * Mode of action**
 * Indications**
 * Major depression
 * Nocturnal enuresis, urge incontinence
 * Adjunct in pain management
 * ADHD (third line treatment)
 * Migraine prophylaxis

Resources
[|AMH - Tricyclic antidepressants]