clotrimazole

=Clotrimazole=

How it works
//Impair biosynthesis of ergosterol for cytoplasmic membrane, inhibiting fungal growth; fungistatic.//

Questions to Ask
What medications? - medical conditions? - allergies? //azole antifungals (possibility of cross-reactivity)//

Safe to use in pregnancy (use a 1-week course)

How to take
//Vaginal cream//, insert 1 applicatorful into the vagina daily at bedtime until contents of the tube are used (10% single dose; 2% 3 doses; 1% 6 doses). //Pessary//, insert 1 pessary into the vagina daily at bedtime until contents of pack used (500 mg single dose; 100 mg 6 doses). //Information on how to insert a pessary can be found [|here]//

- Single dose preparations can assist compliance - All internal preparations should be administered at night. This gives the medicine time to be absorbed and eliminates the possibility of accidental loss, which is more likely to occur if the person is mobile.

Side effects
//Topical azoles are generally well tolerated.// Infrequent: burning, stinging, itch, erythema

Other advice?
- Ensure to complete the course of the treatment, even during menstruation and if symptoms resolve - Wear a sanitary pad overnight as the medicine may leak out. - This cream may damage contraceptive diaphragms and condoms; do not rely on these methods while using this cream. - If a cream is used, it may be applied internally as well as externally to the affected areas.

CMI
[|AMH]