intra-nasal+corticosteroids

=Intra-nasal Corticosteroids=

How it works
Works as an anti-inflammatory at the site of action, reducing hayfever symptoms. They reduce inflammation and decrease mucus production. //Produce local anti-inflammatory effects, decrease capillary permeability and mucus production, and produce vasoconstriction in the nasal mucosa.//

Questions to Ask
What medications? - medical conditions? //severe nasal infection// - allergies?

- Caution in children < 12yrs - Rhinocort (budesonide) is safe to use in pregnancy (Category A), while others are not recommended.

How to take
//Patients should be advised to shake the device and to clear the nasal passages before ////using the nasal spray (the use of a saline nasal// //spray may be helpful).//

//Adult//, 2 sprays into each nostril twice daily. Dose may be reduced to 1 spray into each nostril twice daily when symptoms controlled.
 * Beclomethasone:**

//Adult, child >6 years//, initially 128micrograms into each nostril once daily or 64micrograms into each nostril twice daily; maintenance 32–64 micrograms into each nostril once daily.
 * Budesonide:**

Side effects
//Systemic adverse effects are rare with nasal preparations used at recommended doses.// - nasal stinging, itching, sneezing, sore throat, dry mouth, cough - INCS may cause nasal irritation and bleeding. If significant bleeding occurs stop the INCS and refer for examination and advice.

Other advice?
- For maximal effect INCS should be used regularly and commenced one or two weeks before allergen exposure. - onset of action within 3–7 hours; effective on an as-needed basis; optimum effect after several days of regular use - INCS are first-line therapy for moderate to severe or persistent allergic rhinitis. - They are more effective than oral/intra-nasal/ocular antihistamines and intra-nasal mast cell stabilisers. - For symptom relief INCS may initially be combined with a fast acting medication, i.e. oral/intra-nasal decongestant, oral/intra-nasal antihistamine or intra-nasal anticholinergic. - Can be used long term without atrophy of the nasal mucosa

[|Nasal congestion remedies information]

CMI
Beclomethasone: [|AMH] Beconase Budesonide: [|AMH] Rhinocort